Keenan, Martine et al. published their research in Journal of Medicinal Chemistry in 2012 | CAS: 116332-61-7

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.COA of Formula: C10H10F3NO2

Analogues of Fenarimol Are Potent Inhibitors of Trypanosoma cruzi and Are Efficacious in a Murine Model of Chagas Disease was written by Keenan, Martine;Abbott, Michael J.;Alexander, Paul W.;Armstrong, Tanya;Best, Wayne M.;Berven, Bradley;Botero, Adriana;Chaplin, Jason H.;Charman, Susan A.;Chatelain, Eric;von Geldern, Thomas W.;Kerfoot, Maria;Khong, Andrea;Nguyen, Tien;McManus, Joshua D.;Morizzi, Julia;Ryan, Eileen;Scandale, Ivan;Thompson, R. Andrew;Wang, Sen Z.;White, Karen L.. And the article was included in Journal of Medicinal Chemistry in 2012.COA of Formula: C10H10F3NO2 This article mentions the following:

We report the discovery of nontoxic fungicide fenarimol (1, I) as an inhibitor of Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, and the results of structure-activity investigations leading to potent analogs with low nM IC50s in a T. cruzi whole cell in vitro assay. Lead compounds suppressed blood parasitemia to virtually undetectable levels after once daily oral dosing in mouse models of T. cruzi infection. Compounds are chem. tractable, allowing rapid optimization of target biol. activity and drug characteristics. Chem. and biol. studies undertaken in the development of the fenarimol series toward the goal of delivering a new drug candidate for Chagas disease are reported. In the experiment, the researchers used many compounds, for example, N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7COA of Formula: C10H10F3NO2).

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.COA of Formula: C10H10F3NO2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics