Cao, Shixuan et al. published their research in Organic Chemistry Frontiers in 2022 | CAS: 116332-61-7

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Recommanded Product: 116332-61-7

Visible light-driven [3 + 3] annulation reaction of 2H-azirines with Huisgen zwitterions and synthesis of 1,2,4-triazines was written by Cao, Shixuan;Tang, Tong;Li, Jiatian;He, Zhengjie. And the article was included in Organic Chemistry Frontiers in 2022.Recommanded Product: 116332-61-7 This article mentions the following:

A visible light-driven [3 + 3] annulation reaction of 2H-azirines with in-situ generated Huisgen zwitterions from azodicarboxylates and phosphines was herein described. Under very mild conditions and irradiation of blue LED light, disubstituted 2H-azirines readily undergo a formal [3 + 3] annulation reaction with in-situ generated Huisgen zwitterions, affording polysubstituted dihydro-1,2,4-triazines in 51-97% yields with a broad substrate scope. Mechanistic studies unveil that this annulation reaction proceeded through a cascade sequence of nucleophilic addition, light-driven 1,3-ester migration and aza-Wittig-like cyclization. The light-driven ester migration step was believed to be a photochem. process of an intramol. electron donor-acceptor (EDA) complex. In the experiment, the researchers used many compounds, for example, N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7Recommanded Product: 116332-61-7).

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Recommanded Product: 116332-61-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics