Transamidation of primary amides with amines catalyzed by zirconocene dichloride was written by Atkinson, Benjamin N.;Chhatwal, A. Rosie;Lomax, Helen V.;Walton, James W.;Williams, Jonathan M. J.. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2012.Application of 61189-99-9 This article mentions the following:
Zirconocene dichloride has been shown to be an effective catalyst for the transamidation of primary amides with amines in cyclohexane at 80° in 5-24 h. For favorable substrates, the reaction can be performed at temperatures as low as 30°. In the experiment, the researchers used many compounds, for example, 2,2-Diethoxyacetamide (cas: 61189-99-9Application of 61189-99-9).
2,2-Diethoxyacetamide (cas: 61189-99-9) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Application of 61189-99-9
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics