Organic ligand and solvent free oxidative carbonylation of amine over Pd/TiO2 with unprecedented activity was written by Liu, Shujuan;Dai, Xingchao;Wang, Hongli;Shi, Feng. And the article was included in Green Chemistry in 2019.Recommanded Product: 2387-23-7 This article mentions the following:
A highly active Pd/TiO2 catalyst system was prepared and applied in the oxidative carbonylation of amines to ureas with ultra-low Pd content under organic ligand and solvent free conditions. The catalytic turnover frequencies (TOFs, moles of amines converted per mol of Pd per h) were 126 000 and 250 000 h-1 for the production of diphenylurea and dibenzylurea, resp. An expanded substrate scope including the electron-rich and electron-deficient anilines, primary aliphatic amines, secondary amines was also established. This work offers a straightforward, step economic, and green methodol. for the efficient synthesis of valuable ureas. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Recommanded Product: 2387-23-7).
1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.Recommanded Product: 2387-23-7
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics