Direct coupling of sp3 carbon of alkanes with α,β-unsaturated carbonyl compounds using a copper/hydroperoxide system was written by Lan, Yun;Yang, Chao;Xu, Yun-He;Loh, Teck-Peng. And the article was included in Organic Chemistry Frontiers in 2017.Product Details of 116332-61-7 This article mentions the following:
A new methodol. for the monovalent copper-initiated direct coupling of alkanes and hydroperoxides with unsaturated carbonyl compounds was developed. In this work, α,β-unsaturated carbonyl compounds underwent alkylation and peroxidation to give synthetically useful α-peroxy ketones with wide functional group tolerance. The resulting α-peroxy ketones could be easily transformed into very useful α-hydroxy ketones. In the experiment, the researchers used many compounds, for example, N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7Product Details of 116332-61-7).
N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Product Details of 116332-61-7
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics