Acetyl nitrate mediated conversion of methyl ketones to diverse carboxylic acid derivatives was written by Capilato, Joseph N.;Pellegrinelli, Peter J.;Bernard, Josephine;Schnorbus, Logan;Philippi, Shane;Mattiucci, Joseph;Hoy, Erik P.;Perez, Lark J.. And the article was included in Organic & Biomolecular Chemistry in 2021.COA of Formula: C9H10BrNO2 This article mentions the following:
The development of a novel acetyl nitrate mediated oxidative conversion of Me ketones to carboxylic acid derivatives is described. By analogy to the haloform reaction and supported by exptl. and computational investigation authors propose a mechanism for this transformation. In the experiment, the researchers used many compounds, for example, 4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2COA of Formula: C9H10BrNO2).
4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.COA of Formula: C9H10BrNO2
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics