Modular synthesis of tetra-substituted furans from alkynes, Weinreb amides, and aldehydes was written by Silwal, Sajan;Rahaim, Ronald J.. And the article was included in Tetrahedron Letters in 2015.HPLC of Formula: 116332-61-7 This article mentions the following:
A method for the modular one-pot synthesis of tetra-substituted furans using alkynes, Weinreb amides, and non-enolizable aldehydes was developed. Under this titanium promoted method, furans were prepared in moderate yields with high levels of regioselectivity. The system showed good chemoselectivity tolerating aromatic and aliphatic bromides, chlorides, and fluorides, heteroaromatics, alkenes, and silyl ethers. In the experiment, the researchers used many compounds, for example, N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7HPLC of Formula: 116332-61-7).
N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.HPLC of Formula: 116332-61-7
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics