Hindered internal rotation in N-cycloalkyl amides was written by Nishiyama, Tomihiro;Nagata, Kazui;Yamada, Fukiko. And the article was included in Technology Reports of Kansai University in 1983.Quality Control of N-Cyclopropylformamide This article mentions the following:
Cis and trans conformers were observed for N-cyclopropyl-, N-cyclobutyl-, and N-cyclopentylformamides (I, II, and III, resp.) using 13C NMR. For N-cyclohexyl- and N-cycloheptylformamide, the amide moiety did not show double bond character because of deviations from coplanarity. Free energies of activation of rotation about the amide bond in I, II, and III were determined In the experiment, the researchers used many compounds, for example, N-Cyclopropylformamide (cas: 58644-54-5Quality Control of N-Cyclopropylformamide).
N-Cyclopropylformamide (cas: 58644-54-5) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Quality Control of N-Cyclopropylformamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics