Zhang, Xiangyu et al. published their research in Tetrahedron Letters in 2021 | CAS: 58644-54-5

N-Cyclopropylformamide (cas: 58644-54-5) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Name: N-Cyclopropylformamide

Direct synthesis of quinazolinones via the carbon-supported acid-catalyzed cascade reaction of isatoic anhydrides with amides and aldehydes was written by Zhang, Xiangyu;Luo, Chujun;Chen, Xiaoyong;Ma, Weilin;Li, Bin;Lin, Zirui;Chen, Xiuwen;Li, Yibiao;Xie, Feng. And the article was included in Tetrahedron Letters in 2021.Name: N-Cyclopropylformamide This article mentions the following:

A novel catalytic system is reported for the construction of quinazolinones I (R1 = H, 7-Me, 6-OMe, etc.; R2 = Me, Et, cyclopropyl; R3 = Ph, pyridin-3-yl, cyclohexyl, etc.) via the carbon-supported acid-catalyzed cascade coupling of isatoic anhydrides II with amides R2NHCHO and aldehydes R3CHO. Subsequent selective hydrosilylation of the quinazolinones I using a hydrogen-transfer strategy was also explored to provide dihydroquinazolines III with structural diversity. The developed methodol. proceeds with a broad substrate scope and excellent functional group tolerance and utilizes a reusable catalyst and air as a green oxidant. In the experiment, the researchers used many compounds, for example, N-Cyclopropylformamide (cas: 58644-54-5Name: N-Cyclopropylformamide).

N-Cyclopropylformamide (cas: 58644-54-5) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Name: N-Cyclopropylformamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics