Mechanochemical Divergent Syntheses of Oxindoles and α-Arylacylamides via Controllable Construction of C-C and C-N Bonds by Copper and Piezoelectric Materials was written by Lv, Honggui;Xu, Xinyue;Li, Jing;Huang, Xiaobo;Fang, Guoyong;Zheng, Lifei. And the article was included in Angewandte Chemie, International Edition in 2022.HPLC of Formula: 5339-69-5 This article mentions the following:
The divergent syntheses of α-arylacylamides Ar(C)R1R2C(O)NHAr/Alkyl (Ar = Ph, 2,3-dihydro-1-benzofuran-5-yl, naphthalen-1-yl, thiophen-2-yl, etc.; R1 = Me, H; R2 = Me, F; R1R2 = cyclobutyl; Alkyl = Me, 2-methylpropyl, butyl) and oxindoles I (R3 = Me; R4 = Me; R3R4 = cyclobutyl; Alkyl = Me, 2-methylpropyl) via mechanoredox chem. by using easily accessible α-bromo N-sulfonyl amides ArS(O)2(N)alkylC(O)CR2R3X as starting materials were present. The system consists of a catalytic amount of CuII precatalyst and piezoelec. materials. The highly polarized BaTiO3 or PbTiO3 under mech. agitation can act as an electron donor to realize the recycling of CuII and CuI. Control experiments and d. functional theory calculations have been performed to support the proposed mechanistic rationale for the cascade reactions. In the experiment, the researchers used many compounds, for example, N-Isopropylbenzenesulfonamide (cas: 5339-69-5HPLC of Formula: 5339-69-5).
N-Isopropylbenzenesulfonamide (cas: 5339-69-5) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.HPLC of Formula: 5339-69-5
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics