Month: December 2022

Low temperature bleaching and dyeing properties of modified cellulose fabrics with triazine derivative was written by Xie, Kongliang;Hu, Chuanguo;Zhang, Xufang. And the article was included in Carbohydrate Polymers in 2012.SDS of cas: 10543-57-4 This article mentions the following:

Cellulose fabrics were modified with triazine derivative containing multi-cationic groups, 2,4,6-tri [(2-hydroxy-3-trimethyl-ammonium)propyl]-1,3,5-triazine chloride (Tri-HTAC). Low temperature bleaching of modified cellulose fabrics with tetra acetyl ethylene diamine (TAED), tetra acetyl glycineurea (TAGU) or (N-[4-triethylammoniomethyl]-benzoyl) caprolactam chloride (TBCC) as H₂O₂ activator was investigated. Bleaching properties and mechanisms of three activators were discussed. The dyeing properties and colorimetric data of the bleaching fabrics were investigated. The results show that the modified cellulose fabrics with Tri-HTAC could be bleached with hydrogen peroxide at low temperature, using activators. All whiteness indexes and wettabilities of modified fabrics under low temperature bleaching conditions were significantly higher than those of control samples. The exhaustion of the bleached modified fabrics was significant higher than that of unmodified cellulose fabric. Color degree of all bleaching fabrics with activators was also improved. The fastnesses of bleached fabrics were excellent. The quality of modified fabrics bleached under low temperature activator systems was improved. It has potential application in new composites and cleaner production of cellulose biomaterials. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4SDS of cas: 10543-57-4).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.SDS of cas: 10543-57-4

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

High throughput screening of photocatalytic conversion of pharmaceutical contaminants in water was written by Romao, Joana;Barata, David;Ribeiro, Nelson;Habibovic, Pamela;Fernandes, Hugo;Mul, Guido. And the article was included in Environmental Pollution (Oxford, United Kingdom) in 2017.Recommanded Product: 53902-12-8 This article mentions the following:

The susceptibility for photon-induced degradation of over 800 pharmaceutical compounds present in the LOPAC¹²⁸⁰ library, was analyzed by UV/Vis spectroscopy in the absence or presence of TiO₂ P25 in water. In general, few compounds were effectively degraded in the absence of the TiO₂ photocatalyst (3% of all compounds tested), while in the presence of TiO₂, the majority of compounds was converted, often to a large degree. Differences in degree of degradation are evaluated on the basis of mol. weight, as well as the chem. nature of the drug compounds (functional groups and pharmacol. classes). In general, if the mol. weight increases, the degradation efficacy decreases. Relatively high degrees of conversion can be achieved for (relatively small) mols. with functional groups such as aldehydes, alcs., ketones and nitriles. A low degree of conversion was observed for compounds composed of conjugated aromatic systems. Trends in degradation efficacy on the basis of pharmacol. class, e.g. comparing hormones and opioids, are not obvious. In the experiment, the researchers used many compounds, for example, 2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoic acid (cas: 53902-12-8Recommanded Product: 53902-12-8).

2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoic acid (cas: 53902-12-8) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Recommanded Product: 53902-12-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Expeditious and Chemoselective Synthesis of α-Aryl and α-Alkyl Selenomethylketones via Homologation Chemistry was written by Senatore, Raffaele;Castoldi, Laura;Ielo, Laura;Holzer, Wolfgang;Pace, Vittorio. And the article was included in Organic Letters in 2018.Application of 226260-01-1 This article mentions the following:

Diselenoacetals, previously considered byproducts in homologation tactics en route to α-selenoketones, are herein found to be excellent starting materials for this purpose. The easy selenium/lithium exchange they undergo affords seleno carbanions which are smoothly added to Weinreb amides to chemoselectively prepare α-aryl- and α-alkyl seleno methylketones through a single chem. operation. No racemization events are observed in the presence of optically pure starting materials. In the experiment, the researchers used many compounds, for example, 3-Fluoro-N-methoxy-N-methylbenzamide (cas: 226260-01-1Application of 226260-01-1).

3-Fluoro-N-methoxy-N-methylbenzamide (cas: 226260-01-1) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Application of 226260-01-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Stereoselective Synthesis of the γ-Lactam Hydrolysate of the Thiopeptide Cyclothiazomycin was written by Bagley, Mark C.;Xiong, Xin. And the article was included in Organic Letters in 2004.Related Products of 61189-99-9 This article mentions the following:

Chiral nonracemic thiazolylpropynone enamine I undergoing Bohlmann-Rahtz pyridine synthesis afforded a pyridine-containing γ-amino acid II in high optical purity that proceeded with total control of regiochem. and with minimal racemization. II was further modified to γ-lactam III, hydrolyzate of the macrocyclic thiopeptide antibiotic cyclothiazomycin, a selective renin inhibitor. Thus, III was synthesized in only four steps with 30% overall yield and 88% enantiomeric excess. In the experiment, the researchers used many compounds, for example, 2,2-Diethoxyacetamide (cas: 61189-99-9Related Products of 61189-99-9).

2,2-Diethoxyacetamide (cas: 61189-99-9) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Related Products of 61189-99-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

One-pot synthesis of 1,2,4-oxadiazoles from chalcogen amino acid derivatives under microwave irradiation was written by Wolf, Lucas;Mayer, Joao C. P.;Quoos, Natalia;Sauer, Andre C.;Schwab, Ricardo S.;Rodrigues, Oscar E. D.;Dornelles, Luciano. And the article was included in Tetrahedron in 2021.Recommanded Product: 1,3-Dicyclohexylurea This article mentions the following:

A series of sulfur- and selenium-bearing, amino acid-derived 1,2,4-oxadiazoles were obtained by a simple procedure. The method consists of EDC-promoted coupling of chalcogen amino acid derivatives with arylamidoximes in acetone, followed by solvent removal and microwave irradiation in water medium. Influence of amidoxime substituents, of the chalcogen atom and of the amino acid side chain is discussed. The results showed this to be a fast, easy and effective method to obtain these compounds, with good functional-group tolerance, potentially favoring future applications in organic synthesis. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Recommanded Product: 1,3-Dicyclohexylurea).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Recommanded Product: 1,3-Dicyclohexylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

One-Pot Trifluoromethylative Functionalization of Amides: Synthesis of Trifluoromethylated Bis(indolyl)arylmethanes and Triarylmethanes was written by Pandey, Vinay Kumar;Anbarasan, Pazhamalai. And the article was included in Journal of Organic Chemistry in 2017.Category: amides-buliding-blocks This article mentions the following:

Efficient and general one-pot trifluoromethylative functionalization of amides has been accomplished for the synthesis of various trifluoromethylated bis(indolyl)arylmethane, utilizing trifluoromethyltrimethylsilane and substituted indoles as nucleophiles. The developed reaction involves the in situ generation and trapping of a trifluoromethylated iminium ion, derived from the trifluoromethylated hemiaminal of amide, with various substituted indoles. This method has been successfully extended to the synthesis of diverse trifluoromethylated triarylmethanes employing phenols as nucleophiles. Furthermore, the potential of the method was demonstrated via the two-step synthesis of a trifluoromethylated analog of a hypolipidemic and anti-obesity agent. In the experiment, the researchers used many compounds, for example, 4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2Category: amides-buliding-blocks).

4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Reaction of some N-substituted 1,4-benzoquinone imines with sodium arenesulfinates was written by Konovalova, S. A.;Avdeenko, A. P.;Marchenko, I. L.. And the article was included in Russian Journal of Organic Chemistry in 2014.Safety of N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide This article mentions the following:

N-Arylsulfonyl, N-aroyl, and N-[arylsulfonylimino(phenyl)methyl] derivatives of 1,4-benzoquinone imine reacted with sodium arenesulfinates to give 1,4-, 1,6-, and 6,1-addition products which were formed according to two concurrent paths: direct nucleophilic addition of arenesulfinate anion to neutral quinone imine mol. and radical ion addition of arenesulfinate radical to radical anion derived from quinone imine. In the experiment, the researchers used many compounds, for example, N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide (cas: 1146-43-6Safety of N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide).

N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide (cas: 1146-43-6) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Safety of N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Synthesis of N-aryl substituted p-toluenesulphonamides via nickel catalyzed amidation reaction and their antibacterial, antifungal and antioxidant activities evaluation was written by Izuchukwu, Ugwuja Daniel;Chris, Okoro Uchechukwu;Izuchukwu, Ugwu David. And the article was included in Pakistan Journal of Pharmaceutical Sciences in 2018.Recommanded Product: N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide This article mentions the following:

In present study nickel catalyzed synthesis of N-(aryl) substituted p-toluene sulfonamides is reported. Substituted p-toluene sulfonamides were obtained by coupling 4-methylbenezenesulfonamide with various readily available aryl halides via Buchwald-Hartwig cross-coupling reaction. The new compounds were screened for antibacterial and antifungal activities against Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coll, Staphylococcus aureus, salmonella typhi, candida albicans and Aspergillus niger using agar diffusion technique. The sulfonamides were further screened for antioxidant activity using 1,1-diphenyl-2-picrylhydrazyl, Ferrous sulfate lipid per oxidation and Ferric reducing antioxidant power. Tests such as acute toxicity, liver function and kidney function was also carried out on the synthesized compounds In the experiment, the researchers used many compounds, for example, N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide (cas: 1146-43-6Recommanded Product: N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide).

N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide (cas: 1146-43-6) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Recommanded Product: N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Ameliorative role of Cyanus depressus (M.Bieb.) Sojak plant extract against diabetes-associated oxidative-stress-induced liver, kidney, and pancreas damage in rats was written by Duman, Kendal Erdem;Dogan, Abdulahad;Kaptaner, Burak. And the article was included in Journal of Food Biochemistry in 2022.Category: amides-buliding-blocks This article mentions the following:

In this original article, we aimed to assess the ameliorative role of Cyanus depressus (CD) plant ethanolic extract treatment of streptozotocin (STZ)-induced liver, kidney, and pancreas damage in rats. The rats were divided into five groups (n = 7): control, CD, Diabetes mellitus (DM), DM + CD, and DM + glibenclamide (Gly). The DM groups were injected with a single dose of 50 mg/kg STZ i.p. (i.p.). While the CD and DM + CD groups received 400 mg/kg/day intragastrically for 21 days, the DM + Gly group received 3 mg/kg/day of Gly intragastrically throughout the experiment Statistically significance was accepted as p < .05. According to our liquid chromatog.-mass spectrometry/mass spectrometry (LC-MS/MS) data, quinic acid, cosmosiin, nicotiflorin, apigenin, and protocatechuic acid were the major compounds, in descending order. Weekly blood glucose, serum glucose, aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH) and urea, malondialdehyde (MDA) (liver and pancreas), and blood glycosylated Hb % (HbA1c %) were significantly decreased, whereas finally live body weights (LBWs), reduced glutathione (GSH), glutathione S-transferase (GST) and catalase (CAT) (pancreas), and pancreatic islet diameter and area were increased significantly in the CD-treated diabetic group. Moreover, CD administration was found to be effective in the protection of the histol. of the liver, kidneys, and pancreatic islets in the STZ-induced rats. Consequently, we concluded that CD administration reduces hyperglycemia, oxidative stress, and histopathol. in STZ-induced exptl. rats by improving antioxidant defenses. Practical applications : Today, the prevalence of diabetes is increasing rapidly throughout the world and it causes complications such as kidney damage, blindness, amputations, and cardiovascular diseases. Despite medical technol. advances, people′s interest in medicinal herbal products is gradually increasing. Biochem. and histopathol. findings showed that the use of the plant CD at the determined dose (400 mg/kg/day) in rats with DM by STZ had strong antioxidant and antidiabetic effects. CD may have a drug potential in preventing DM and its complications because of its phytochem. content including some phenolic acids such as quinic acid, cosmosiin, nicotiflorin, apigenin, and protocatechuic acid. Isolation of bioactive compounds from CD and investigation of their therapeutic effects could be planned as further studies. In the experiment, the researchers used many compounds, for example, 5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide (cas: 10238-21-8Category: amides-buliding-blocks).

5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide (cas: 10238-21-8) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Enzymatic desizing, bioscouring and enzymatic bleaching of cotton fabric with glucose oxidase was written by Mojsov, Kiro. And the article was included in Journal of the Textile Institute in 2019.Recommanded Product: 10543-57-4 This article mentions the following:

The sized cotton fabric was enzymically desized, scoured and bleached with an enzyme mixture of starch degrading enzymes, pectinases and glucose oxidases (GOxs) was added to generate hydrogen peroxide (HP). In this study, enzyme selection and process optimization was made in order to increase the glucose content of the desizing liquor of a starch-sized cotton fabric. The highest glucose concentration of 4175 mg/L was measured in one-bath containing mixture of α-amylase, amyloglucosidase and pectinase and GOx produced 758 mg/L peroxide. This combination was used in further bleaching processes. For bleaching, hydrogen peroxide was converted into peracetic acid (PAA) by incorporating the bleach activator tetraacetylethylenediamine (TAED). Whiteness values, water absorbency, polymerization degree and tenacity at maximum load were measured on pre-treated samples. The total organic carbon (TOC), COD (COD), biol. oxygen demand (BOD₅), the biol. degradability (BOD₅/COD) and the final pH values were measured on residual pre-treatment baths. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Recommanded Product: 10543-57-4).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Recommanded Product: 10543-57-4

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics