Gold-Catalyzed Intermolecular [4+2] Annulation of 2-Ethynylanilines with Ynamides: An Access to Substituted 2-Aminoquinolines was written by Zhao, Ximei;Song, Xinlong;Jin, Hongming;Zeng, Zhongyi;Wang, Qian;Rudolph, Matthias;Rominger, Frank;Hashmi, A. Stephen K.. And the article was included in Advanced Synthesis & Catalysis in 2018.Computed Properties of C9H13NO2S This article mentions the following:
A gold-catalyzed intermol. [4+2] annulation of easily accessible 2-ethynylanilines with ynamides offered a highly regioselective, modular, efficient and atom-economical strategy for the synthesis of substituted 2-aminoquinolines such as I [R1 = H, 6-F, 6-Cl, 6-CF3, 6-Me; R2 = Ph, 4-MeOC6H4, 2-thienyl, etc.; R3 = Me, n-Pr, Bn, etc.; R4 = Tosyl, Mesyl, Benzenesulfonyl] in up to 93% yield. In the experiment, the researchers used many compounds, for example, N-Isopropylbenzenesulfonamide (cas: 5339-69-5Computed Properties of C9H13NO2S).
N-Isopropylbenzenesulfonamide (cas: 5339-69-5) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Computed Properties of C9H13NO2S
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics