High throughput screening of photocatalytic conversion of pharmaceutical contaminants in water was written by Romao, Joana;Barata, David;Ribeiro, Nelson;Habibovic, Pamela;Fernandes, Hugo;Mul, Guido. And the article was included in Environmental Pollution (Oxford, United Kingdom) in 2017.Recommanded Product: 53902-12-8 This article mentions the following:
The susceptibility for photon-induced degradation of over 800 pharmaceutical compounds present in the LOPAC1280 library, was analyzed by UV/Vis spectroscopy in the absence or presence of TiO2 P25 in water. In general, few compounds were effectively degraded in the absence of the TiO2 photocatalyst (3% of all compounds tested), while in the presence of TiO2, the majority of compounds was converted, often to a large degree. Differences in degree of degradation are evaluated on the basis of mol. weight, as well as the chem. nature of the drug compounds (functional groups and pharmacol. classes). In general, if the mol. weight increases, the degradation efficacy decreases. Relatively high degrees of conversion can be achieved for (relatively small) mols. with functional groups such as aldehydes, alcs., ketones and nitriles. A low degree of conversion was observed for compounds composed of conjugated aromatic systems. Trends in degradation efficacy on the basis of pharmacol. class, e.g. comparing hormones and opioids, are not obvious. In the experiment, the researchers used many compounds, for example, 2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoic acid (cas: 53902-12-8Recommanded Product: 53902-12-8).
2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoic acid (cas: 53902-12-8) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Recommanded Product: 53902-12-8
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics