A mild and convenient oxidation of aryl nitriles to aryl amides by aqueous sodium perborate was written by Reed, Kathryn L.;Gupton, John T.;Solarz, Traci L.. And the article was included in Synthetic Communications in 1990.Name: 3,4-Dichlorobenzamide This article mentions the following:
Treatment of aryl nitriles with NaBO3.4H2O in aqueous dioxane gives the corresponding benzamides in 13-85% yields. E.g., 3,5-Cl2C6H3CN gives 74% 3,5-Cl2C6H3CONH2. The effect of substrate structure on yield is discussed. In the experiment, the researchers used many compounds, for example, 3,4-Dichlorobenzamide (cas: 2670-38-4Name: 3,4-Dichlorobenzamide).
3,4-Dichlorobenzamide (cas: 2670-38-4) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Name: 3,4-Dichlorobenzamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics