Wang, Bin’s team published research in Journal of Heterocyclic Chemistry in 57 | CAS: 372136-76-0

Journal of Heterocyclic Chemistry published new progress about 372136-76-0. 372136-76-0 belongs to amides-buliding-blocks, auxiliary class Sulfamide,Amine,Aliphatic hydrocarbon chain, name is N-Methyl-N-isopropylsulfamoyl amide, and the molecular formula is C4H6O3, Safety of N-Methyl-N-isopropylsulfamoyl amide.

Wang, Bin published the artcileNew and convergent synthesis of saflufenacil, Safety of N-Methyl-N-isopropylsulfamoyl amide, the publication is Journal of Heterocyclic Chemistry (2020), 57(1), 151-156, database is CAplus.

A new practical and hundred-gram scale synthesis of saflufenacil, a protoporphyrinogen oxidase (PPO) inhibitor herbicide was described. The key intermediate N-methyl-N-iso-Pr sulfamide was obtained from sulfuryl chloride isocyanate, t-butanol and N-methyl-N-isopropylamine in 74.8% yield over 3 steps. Saflufenacil was prepared in 48.6% yield over 8 steps and 98.7% purity (HPLC).

Journal of Heterocyclic Chemistry published new progress about 372136-76-0. 372136-76-0 belongs to amides-buliding-blocks, auxiliary class Sulfamide,Amine,Aliphatic hydrocarbon chain, name is N-Methyl-N-isopropylsulfamoyl amide, and the molecular formula is C4H6O3, Safety of N-Methyl-N-isopropylsulfamoyl amide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics