Waisser, Karel published the artcileBiological side effects of potential antituberculotics. XV. Quantitative relations between chemical structure and hepatotoxicity of thiobenzamides, Safety of 3-Methoxybenzothioamide, the publication is Collection of Czechoslovak Chemical Communications (1988), 53(11B), 2957-61, database is CAplus.
1H NMR chem. shifts. of thioamide protons have been determined for a group of thiobenzamides, and the values obtained have been correlated with the Hammett constants From the relations found, the σm and σp values of the thioamide group and some other σ constants describing the total effect of 2 substituents in the Ph group have been calculated The relation between the hepatotoxicity for rats [expressed as log ALT (serum alaninoaminotransferase)] and the Hammett constants is described by the parabolic equation.
Collection of Czechoslovak Chemical Communications published new progress about 64559-06-4. 64559-06-4 belongs to amides-buliding-blocks, auxiliary class Amine,Benzene,Amide,Ether, name is 3-Methoxybenzothioamide, and the molecular formula is C7H10N2O2, Safety of 3-Methoxybenzothioamide.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics