Tung, Truong Thanh published the artcileAmide bond formation in aqueous solution: direct coupling of metal carboxylate salts with ammonium salts at room temperature, Quality Control of 79-07-2, the publication is Organic & Biomolecular Chemistry (2021), 19(46), 10073-10080, database is CAplus and MEDLINE.
A green, expeditious and practically simple protocol for direct coupling of carboxylate salts such as sodium benzoate, sodium nicotinate, sodium acrylate, etc. and ammonium salts such as methoxyamine hydrochloride, ammonium chloride, dimethylamine hydrochloride, etc. under ACN/H2O conditions at room temperature without the addition of tertiary amine bases was reported. The water-soluble coupling reagent EDC·HCl is a key component in the reaction. The reaction runs smoothly with unsubstituted/substituted ammonium salts and provides a clean products e.g., N-methoxybenzamide without column chromatog. This reaction tolerates both carboxylate (which are unstable in other forms) and amine salts (which are unstable/volatile when present in free form). It was believed that the reported method could be used as an alternative and suitable method at the laboratory and industrial scales.
Organic & Biomolecular Chemistry published new progress about 79-07-2. 79-07-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Aliphatic hydrocarbon chain,Amide,Inhibitor, name is 2-Chloroacetamide, and the molecular formula is C5H5BrN2, Quality Control of 79-07-2.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics