Tang, A-ping’s team published research in Nongyao in 52 | CAS: 372136-76-0

Nongyao published new progress about 372136-76-0. 372136-76-0 belongs to amides-buliding-blocks, auxiliary class Sulfamide,Amine,Aliphatic hydrocarbon chain, name is N-Methyl-N-isopropylsulfamoyl amide, and the molecular formula is C9H8BNO2, Application of N-Methyl-N-isopropylsulfamoyl amide.

Tang, A-ping published the artcileSynthesis of N-methyl-N-isopropyl sulfonamide, Application of N-Methyl-N-isopropylsulfamoyl amide, the publication is Nongyao (2013), 52(10), 721-722, 725, database is CAplus.

This article aims to explore and optimize a reasonable synthesis route of N-methyl-N-iso-Pr sulfonamide on industrial scale. Amino sulfonyl chloride was synthesized from chlorosulfonyl isocyanate and aqueous formic acid, then reacted with N-methy-N-iso-Pr amine to get the target product. The total yield was 62.7%. The products and intermediates were determined by 1H NMR and MS and so on. The yield is improved and the process is simplified, which can be used in industry.

Nongyao published new progress about 372136-76-0. 372136-76-0 belongs to amides-buliding-blocks, auxiliary class Sulfamide,Amine,Aliphatic hydrocarbon chain, name is N-Methyl-N-isopropylsulfamoyl amide, and the molecular formula is C9H8BNO2, Application of N-Methyl-N-isopropylsulfamoyl amide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics