Stolley, Ryan M.'s team published research in European Journal of Organic Chemistry in 2011

Stolley, Ryan M. published the artcileNickel-Catalyzed [2+2+2] Cycloaddition of Diynes and Cyanamides, SDS of cas: 2451-91-4, the publication is European Journal of Organic Chemistry (2011), 2011(20-21), 3815-3824, database is CAplus and MEDLINE.

A variety of bicyclic N,N-disubstituted 2-aminopyridines have been prepared from diynes and cyanamides by nickel-catalyzed [2+2+2] cycloaddition reactions. The reactions proceeded at room temperature with low catalyst loading to afford 2-aminopyridines in good to excellent yields. E.g., in presence of Ni(cod)₂ and IMes [1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene], [2+2+2] cycloaddition of MeCCCH₂C(CO₂Me)₂CH₂CCMe and N-cyanopyrrolidine gave 98% 2-aminopyridine derivative I. The method is amenable to both internal and terminal diynes and proceeds in a regioselective manner. A number of cyanamides with diverse functional group tolerance were used. The intermol. version employing 3-hexyne and N-cyanopyrrolidine also afforded the desired N,N-disubstituted 2-aminopyridine in good yield.

European Journal of Organic Chemistry published new progress about 2451-91-4. 2451-91-4 belongs to amides-buliding-blocks, auxiliary class Nitrile,Amine,Benzene, name is N,N-Dibenzylcyanamide, and the molecular formula is C5H7N3S3, SDS of cas: 2451-91-4.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics