Shi, Xiaoyu published the artcileLabel-retention expansion microscopy, Recommanded Product: H-Lys(Boc)-OH, the publication is Journal of Cell Biology (2021), 220(9), e202105067, database is CAplus and MEDLINE.
Expansion microscopy (ExM) increases the effective resolving power of any microscope by expanding the sample with swellable hydrogel. Since its invention, ExM has been successfully applied to a wide range of cell, tissue, and animal samples. Still, fluorescence signal loss during polymerization and digestion limits mol.-scale imaging using ExM. Here, we report the development of label-retention ExM (LR-ExM) with a set of trifunctional anchors that not only prevent signal loss but also enable high-efficiency labeling using SNAP and CLIP tags. We have demonstrated multicolor LR-ExM for a variety of subcellular structures. Combining LR-ExM with superresoln. stochastic optical reconstruction microscopy (STORM), we have achieved mol. resolution in the visualization of polyhedral lattice of clathrin-coated pits in situ.
Journal of Cell Biology published new progress about 2418-95-3. 2418-95-3 belongs to amides-buliding-blocks, auxiliary class Chiral,Carboxylic acid,Amine,Aliphatic hydrocarbon chain,Ester,Amino acide derivatives, name is H-Lys(Boc)-OH, and the molecular formula is C37H30ClIrOP2, Recommanded Product: H-Lys(Boc)-OH.
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