Hostyn, Steven published the artcileSynthesis of the benzo-β-carboline isoneocryptolepine: the missing indoloquinoline isomer in the alkaloid series cryptolepine, neocryptolepine and isocryptolepine, HPLC of Formula: 146140-95-6, the publication is Tetrahedron (2005), 61(6), 1571-1577, database is CAplus.
7H-Indolo[2,3-c]quinoline has been synthesized in two steps via a new approach starting from com. available 3-bromoquinoline and 2-bromoaniline. The new methodol. consists of two consecutive palladium-catalyzed reactions: a selective Buchwald/Hartwig amination followed by an intramol. Heck-type reaction. Alternatively, the same skeleton has also been prepared via the combination of a Suzuki arylation with an intramol. nitrene insertion starting from 4-chloroquinoline and {2-[(2,2-dimethylpropanoyl)amino]phenyl}boronic acid. Selective methylation of 7H-indolo[2,3-c]quinoline yielded 5-methyl-5H-indolo[2,3-c]quinoline (isoneocryptolepine, I) which is an interesting new lead compound in the search for new antiplasmodial drugs.
Tetrahedron published new progress about 146140-95-6. 146140-95-6 belongs to amides-buliding-blocks, auxiliary class Boronic acid and ester,Amine,Benzene,Amide,Boronic Acids,Boronic Acids,Boronic acid and ester,, name is (2-Pivalamidophenyl)boronic acid, and the molecular formula is C11H16BNO3, HPLC of Formula: 146140-95-6.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics