Fu, Niankai’s team published research in Organic Letters in 16 | CAS: 1869-45-0

Organic Letters published new progress about 1869-45-0. 1869-45-0 belongs to amides-buliding-blocks, auxiliary class Trifluoromethylated Building Blocks, name is 2,2,2-Trifluoro-N-(2-mercaptoethyl)acetamide, and the molecular formula is C4H6F3NOS, HPLC of Formula: 1869-45-0.

Fu, Niankai published the artcileAsymmetric Sulfa-Michael Addition to α-Substituted Vinyl Ketones Catalyzed by Chiral Primary Amine, HPLC of Formula: 1869-45-0, the publication is Organic Letters (2014), 16(17), 4626-4629, database is CAplus and MEDLINE.

The first effective example of asym. conjugate addition-protonation reactions of thiols to α-substituted vinyl ketones by chiral primary amine catalysis is reported. A simple chiral primary-tertiary diamine catalyst derived from L-phenylalanine, I, was found to promote the sulfa-Michael addition-protonation reactions with good to excellent enantioselectivity. Thus, reacting thiol F3CCONH(CH2)2SH with MeC(COPh):CH2 in the presence of I gave sulfur-containing amide-ketone II.

Organic Letters published new progress about 1869-45-0. 1869-45-0 belongs to amides-buliding-blocks, auxiliary class Trifluoromethylated Building Blocks, name is 2,2,2-Trifluoro-N-(2-mercaptoethyl)acetamide, and the molecular formula is C4H6F3NOS, HPLC of Formula: 1869-45-0.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics