Zhao, Yigang published the artcileC-H Activation by Amide Chelation Control: Ruthenium-Catalyzed Direct Synthesis of 2-Aryl-3-furanamides, Formula: C10H14N2O, the publication is Advanced Synthesis & Catalysis (2014), 356(7), 1527-1532, database is CAplus.
A new, catalytic methodol. for the synthesis of heterobiaryls by the ruthenium-catalyzed C-H activation/cross-coupling of heterocyclic amides with 2-aryl-1,3,2-dioxaborinanes is surveyed. From this survey, the highly regioselective reaction of furan-3-carboxamide to give 2-aryl-3-furanamides is optimized and generalized in scope with respect to the 2-aryl-1,3,2-dioxaborinane partners. E.g., in presence of RuH2(CO)(PPh3)3 in toluene, reaction of N,N-diethylfuran-3-carboxamide with 2-aryl-1,3,2-dioxaborinane derivative (I) gave 92% heterobiaryl (II). Established thereby is a one-step synthetic method which may supercede the broadly applied two-step directed ortho metalation (DoM)-cross coupling reaction involving cryogenic and strong base conditions and which has potential for further ortho and remote metalation chem.
Advanced Synthesis & Catalysis published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C11H10N4, Formula: C10H14N2O.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics