Wang, Chunxiang published the artcileIron-Catalyzed Cycloaddition Reaction of Diynes and Cyanamides at Room Temperature, Formula: C15H14N2, the publication is Journal of Organic Chemistry (2013), 78(7), 3065-3072, database is CAplus and MEDLINE.
An iron-catalyzed [2+2+2] cycloaddition reaction of diynes and cyanamides at room temperature is reported. Highly substituted 2-aminopyridines were obtained in good to excellent yields with high regioselectivity. E.g., in presence of FeI2, dppp, and Zn dust, [2+2+2] cycloaddition reaction of MeCCCH2NTsCH2CCMe and (Me2CH)2NCN gave 91% 2-aminopyridine derivative (I). Insights toward the reaction process were investigated through in situ IR spectra and control experiments In this iron-catalyzed cycloaddition reaction, the active iron species was generated only in the presence of both alkynes and nitriles. The lower reaction temperature, broad substrates scope, and inversed regioselectivity make it a complementary method to the previously developed iron catalytic system.
Journal of Organic Chemistry published new progress about 2451-91-4. 2451-91-4 belongs to amides-buliding-blocks, auxiliary class Nitrile,Amine,Benzene, name is N,N-Dibenzylcyanamide, and the molecular formula is C8H5F3N4, Formula: C15H14N2.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics