Rao, G. Venkateswara published the artcilePreferential reactivity of pyridylmagnesium chloride with N,N-dialkyl arylamides over carbonitriles: synthesis of 2-(aroyl) pyridines, COA of Formula: C10H14N2O, the publication is Synthetic Communications (2009), 39(10), 1835-1846, database is CAplus.
Reaction of 2-pyridylmagnesium chlorides with N,N-dialkyl arylamides afford exclusively 2-(aroyl)pyridines in high yields and purity without the formation of any tertiary alc. This method employs easily available raw materials and avoids the use of hazardous lithium reagents and cryogenic conditions. Further, preferential reactivity of this Grignard reagent with N,N-dialkyl arylamides over its carbonitrile counterparts offers a variety of 2-(aroyl)pyridines including the ones containing carbonitrile groups on the aryl ring.
Synthetic Communications published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H14N2O, COA of Formula: C10H14N2O.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics