Li, Qing Yu published the artcileT-shaped trifunctional crosslinker-toughening hydrogels, Name: N-(2-Amino-2-oxoethyl)acrylamide, the publication is Science China: Technological Sciences (2020), 63(9), 1721-1729, database is CAplus.
Abstract: Currently, development of a single network hydrogel with a high fracture toughness in swelling equilibrium remains challenging. In this work, a novel T-shaped trifunctional crosslinker (T-NAGAX) with dual vinyl on the backbone and dual amide group on the side chain is synthesized by Michael addition and acylation. The T-NAGAX is used to prepare chem. crosslinked hydrogel by one-pot photo-initiated polymerization The resulting single network hydrogels of representative polyacrylamide (PAAm), poly(N-acryloyl 2-glycine) (PACG), and poly(N-iso-Pr acrylamide) (PNIPAM) crosslinked with T-NAGAX with addnl. hydrogen-bonds exhibit much better fracture toughness than that of the corresponding hydrogels crosslinked by N,N’ -methylene bisacrylamide, a conventional crosslinker; higher mech. strengths are observed in the T-NAGAX crosslinked hydrogels. These hydrogels are promising to be exploited as load-bearing soft tissue substitutes. This T-NAGAX crosslinker can be expanded to toughen various types of hydrogels.
Science China: Technological Sciences published new progress about 2479-62-1. 2479-62-1 belongs to amides-buliding-blocks, auxiliary class Monomers,Acrylamide Monomers, name is N-(2-Amino-2-oxoethyl)acrylamide, and the molecular formula is C5H8N2O2, Name: N-(2-Amino-2-oxoethyl)acrylamide.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics