Li, AnRong’s team published research in Chinese Journal of Chemistry in 11 | CAS: 360-92-9

Chinese Journal of Chemistry published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C6H10F3NO, Recommanded Product: N,N-Diethyl-2,2,2-trifluoroacetamide.

Li, AnRong published the artcileA convenient trifluoroacetylation of amines with trifluoroacetic acid and titanium tetrachloride, Recommanded Product: N,N-Diethyl-2,2,2-trifluoroacetamide, the publication is Chinese Journal of Chemistry (1993), 11(2), 190-2, database is CAplus.

Treating R1R2NH (R1 = H, R2 = Ph, cyclohexyl, allyl, Me2CHCH2, 2-NH2C6H4, 2-HOC6H4; R1 = R2 = Et; R1 = Ph, R2 = Me) with CF3CO2H, 2 equiv Et3N, and 2 equiv TiCl4 in Et2O, MeCN, or CH2Cl2 gave 40-75% R1R2NCOCF3 (same R1, R2); in the case of o-phenylenediamine, the product is 2-(trifluoroacetyl)benzimidazole.

Chinese Journal of Chemistry published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C6H10F3NO, Recommanded Product: N,N-Diethyl-2,2,2-trifluoroacetamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics