Suzuki, Hirotsugu published the artcileDealkoxylation of N-alkoxyamides without an external reductant driven by Pd/Al cooperative catalysis, Synthetic Route of 100377-32-0, the publication is Organic & Biomolecular Chemistry (2020), 18(38), 7545-7548, database is CAplus and MEDLINE.
Lewis acid-assisted palladium-catalyzed dealkoxylation of N-alkoxyamides has been developed. This reaction proceeded smoothly with a range of N-alkoxyamides in the absence of an external reductant, thereby establishing a convenient and reductant-free protocol. In addition, a gram-scale reaction could be achieved. Preliminary mechanistic investigations indicated that β-hydrogen elimination from a palladium alkoxide intermediate generated an intramol. hydride source.
Organic & Biomolecular Chemistry published new progress about 100377-32-0. 100377-32-0 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N-Methoxy-N-methylisonicotinamide, and the molecular formula is C9H9BrO2, Synthetic Route of 100377-32-0.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics