Sattler, H. J. published the artcileStructure-activity relations in analeptics of nicethamide type. I. Diethylamides of homologs and vinylogs of nicotinic and isonicotinic acids, Computed Properties of 530-40-5, the publication is Arzneimittel-Forschung (1974), 24(5), 743-6, database is CAplus and MEDLINE.
The diethylamides I and II (bond in 3 or 4 position, Z = bond, CH2, CH2CH2, or CH:CH) were prepared and showed respiratory analeptic activities in rabbits. I were prepared in 68-76% yield by reaction of the corresponding pyridinecarboxylic acid with ClCO2Et and Et2NH. II were prepared by reaction of acetylpyridines with MeONa and HCO2Et and subsequently with Et2NH.
Arzneimittel-Forschung published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H14N2O, Computed Properties of 530-40-5.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics