Herrero, A. published the artcileDetermination of dichlobenil and its major metabolite (BAM) in onions by PTV-GC-MS using PARAFAC2 and experimental design methodology, Related Products of amides-buliding-blocks, the publication is Chemometrics and Intelligent Laboratory Systems (2014), 92-108, database is CAplus.
The optimization of a GC-MS anal. procedure which includes derivatization, Quick Easy Cheap Effective Rugged and Safe (QuEChERS) and programmed temperature vaporization (PTV) using design of experiments is performed to determine 2,6-dichlorobenzonitrile (dichlobenil) and 2,6-dichlorobenzamide (BAM) in onions, using 3,5-dichlorobenzonitrile and 2,4-dichlorobenzamide as internal standards The use of a central composite design and two D-optimal designs, together with the desirability function, makes it possible to significantly reduce the economic, time and environmental cost of the study. The usefulness of PARAFAC2 for solving problems as the interference of unexpected derivatization artifacts unavoidably linked to some derivatization agents, or the presence of coeluents from the complex matrix, which share m/z ratios with the target compounds, is shown. The limits of decision (CCα) of the optimized procedure, 5.00 μg kg– 1 for dichlobenil and 1.55 μg kg– 1 for BAM (α = 0.05), are below the maximum residue limit (MRL) established by the EU for dichlobenil (20 μg kg– 1) in this commodity.
Chemometrics and Intelligent Laboratory Systems published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H5Cl2NO, Related Products of amides-buliding-blocks.
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https://en.wikipedia.org/wiki/Amide,
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