Arzel, Erwan published the artcileA new synthesis of α-substituted δ-carbolines, Synthetic Route of 146140-95-6, the publication is Journal of Heterocyclic Chemistry (1997), 34(4), 1205-1210, database is CAplus.
A new general synthesis of α-substituted δ-carbolines I [R = H, Me, Et, Ph, 2-H2NC6H4, 2-pyridyl, 2-thienyl, 2-quinolyl], based on key steps such as metalation, cross-coupling and cyclization, was described. E.g., amide II (R = H) was methylated with MeI after lithiation with BuLi. The methylated amide II (R = Me) underwent acid hydrolysis to form the corresponding deprotected amine, which was then converted to δ-carboline I (R = Me) by refluxing in anhydrous pyridinium chloride at 215° followed by hydrolysis with concentrated ammonia at 0°.
Journal of Heterocyclic Chemistry published new progress about 146140-95-6. 146140-95-6 belongs to amides-buliding-blocks, auxiliary class Boronic acid and ester,Amine,Benzene,Amide,Boronic Acids,Boronic Acids,Boronic acid and ester,, name is (2-Pivalamidophenyl)boronic acid, and the molecular formula is C11H16BNO3, Synthetic Route of 146140-95-6.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics