Zhang, Nan published the artcileEffect of surface functionality of molecularly imprinted composite nanospheres on specific recognition of proteins, Related Products of amides-buliding-blocks, the publication is Materials Science & Engineering, C: Materials for Biological Applications (2020), 111076, database is CAplus and MEDLINE.
The surface functionality of biomaterial plays a primary role in determining its application in biorecognition and drug delivery. In our work, three types of synthetic tailoring polymer nanospheres with hierarchical architecture were constructed to obtain functional polymer layer with disparate chem. motifs for protein adsorption via surface imprinting and grafting copolymerization In this polymerization system, the structure stability of template protein bovine serum albumin (BSA) is well maintained within a certain range, which facilitated the accurate imprinting and precise identification. A comprehensive protocol for screening different functional layer is proposed through comparing the adsorption behavior, selectivity, identification and responsiveness to medium pH of three functional layers. Our study demonstrates that surface functionality greatly influences the adsorption capacity and selectivity of adsorption material. The functional layer with ionic liquid structure that could only provide multiple non-covalent binding sites is beneficial to the proteins aggregation and extraction, while the anti-nonspecific binding functional layer of biomaterial with zwitterionic structure for specific protein capture is promising to serve as a preferable antigen-antibody communication network, which shows great potential for protein recognition and separation In summary, our proposed strategy provides a systematic selection criterion of biomaterials for effective application in biosensors.
Materials Science & Engineering, C: Materials for Biological Applications published new progress about 79-07-2. 79-07-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Aliphatic hydrocarbon chain,Amide,Inhibitor, name is 2-Chloroacetamide, and the molecular formula is C11H12O4, Related Products of amides-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics