Wang, Xuan published the artcilePreparation and evaluation of polyphenol derivatives as potent antifouling agents: addition of a side chain affects the biological activity of polyphenols, Application of 2-Chloroacetamide, the publication is Biofouling (2022), 38(1), 29-41, database is CAplus and MEDLINE.
In this study, eight polyphenol derivatives were prepared to serve as green antifoulants. Polyphenol derivatives, which can hinder the growth of bacteria and algae and decrease the adhesion of some marine organisms, showed good AF activity; in particular, the activities of these derivatives were much higher than those of the corresponding polyphenols. The antibacterial rates of the products (20μg ml-1) exceeded 88%. Moreover, the anti-algal rates of compounds a3, b1, b2, b3 and b4 (15μg ml-1) were over 57% at 240 h, but these compounds showed low toxicity, and the 120 h EC50 values were > 6.60μg ml-1. In addition, there were fewer marine microorganisms on the test panel than on the control. The above results show that some polyphenol derivatives possess relatively high antibacterial, anti-algal, and AF activity; more notably, the addition of chlorine atoms and amide groups can further increase the activity of these derivatives
Biofouling published new progress about 79-07-2. 79-07-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Aliphatic hydrocarbon chain,Amide,Inhibitor, name is 2-Chloroacetamide, and the molecular formula is C7H8BFO2, Application of 2-Chloroacetamide.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics