Takatori, Kichitaro published the artcileSyntheses of amides derived from heterocyclic acids and heterocyclic amines and their antitumor activities, Application In Synthesis of 51987-99-6, the publication is Yakugaku Zasshi (1976), 96(4), 471-4, database is CAplus and MEDLINE.
Pyridineacetamides I, II (R = 3-, 4-pyridyl) and 12 thiadiazoles (III, R = 3-,4-pyridyl, 2-thienyl, 2-furyl; R1 = H, CHMe2, CH2CHMe2) were prepared from the phenyl esters of heterocyclic acids and heterocyclic amines preparation procedure not given in the original. III (R = 4-pyridyl, R1 = H, CHMe2, CH2CHMe2; R = 3-pyridyl, R1 = CHMe2, R = 2-thienyl, R1 = CHMe2CH2CHMe2; R = 2-furyl, R1 = CHMe2, CH2CHMe2) had slight antitumor activity against Ehrlich ascites carcinoma and crocker sarcoma-180 in mice.
Yakugaku Zasshi published new progress about 51987-99-6. 51987-99-6 belongs to amides-buliding-blocks, auxiliary class Pyridine,Thiadiazole,Amine,Amide,Inhibitor, name is N-(1,3,4-Thiadiazol-2-yl)nicotinamide, and the molecular formula is C42H63O3P, Application In Synthesis of 51987-99-6.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics