Leonov, O. N.’s team published research in Zhurnal Obshchei Khimii in 62 | CAS: 360-92-9

Zhurnal Obshchei Khimii published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C6H10F3NO, Formula: C6H10F3NO.

Leonov, O. N. published the artcileSynthesis and properties of N2-acylated polyfluoroalkanamidines, Formula: C6H10F3NO, the publication is Zhurnal Obshchei Khimii (1992), 62(7), 1592-7, database is CAplus.

Acylating HN:C(CF3)NR2 (I; R = Me, Et) with R1COCl (R1 = CF3, CHF2, C2F5) in Et2O containing Et3N gave 5 corresponding R1CON:C(CF3)NR2 in 64.1-89.1% yield. Analogous reaction of CF3COCl with HN:C(CF3)NHMe (II) gave CF3CON:C(CF3)NHMe and CF3CONHC(CF3):NMe in 45.2% combined yield, and (CF3)2C:CO (III) and II gave 86.4% (CF3)2CHCON:C(CF3)NHMe. I (same R) and HN:C(C2F5)NEt2 added to III to give 64.1-93.4% (CF3)2CHCON:CR2NR2 [R = Me, Et (IV), R2 = CF3; R = Et, R2 = C2F5], and IV was hydrolyzed to (CF3)2CHCONH2 and CF3CONEt2. IR and 1H and 19F NMR data were given for all title products.

Zhurnal Obshchei Khimii published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C6H10F3NO, Formula: C6H10F3NO.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics