Eccles, Peter J. published the artcileOrganophosphorus compounds as potential fungicides. Part IV. The preparation and properties of some novel N-(1-substituted-2,2,2-trichloroethyl)phosphoramidates, Synthetic Route of 2447-79-2, the publication is Phosphorus, Sulfur and Silicon and the Related Elements (1995), 105(1-4), 33-44, database is CAplus.
A series of 20 di-Et N-(1-substituted-2,2,2-trichloroethyl)phosphoramidates (EtO)2P(O)NHCH(CCl3)X was prepared containing N-heterocyclic, carboxamide, phosphoramide, dithiocarbamate, xanthate, and hydroxyethylthio substituents X in the 1-position of the 2,2,2-trichloroethyl group. Screening in vitro at 500 ppm showed the dithiocarbamates (EtO)2P(O)NHCH(CCl3)SCSNR2 (R = Me, Et) to be the most active, giving complete control of Fusarium spp., Helminthosporium spp., and Ophiobolus graminis under these conditions. High activity was also observed against Fusarium culmorum for the triazole, hydroxyethylthio, and xanthate derivatives, and for an imidazole analog in which one ethoxy and one dimethylamino group were attached to phosphorus. The carboxamide derivatives were the least active. The dithiocarbamates also gave ca. 50% control of Piricularia oryzae and Rhizoctonia solani at 300 ppm in vitro. Lower levels of activity were recorded when the compounds were applied to seeds infected with Drechslera teres and Septoria nodorum and slight inhibition of germination and plant development was observed The compounds were all weak inhibitors of acetylcholinesterase.
Phosphorus, Sulfur and Silicon and the Related Elements published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H5Cl2NO, Synthetic Route of 2447-79-2.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics