Collins, Scott’s team published research in Journal of Organic Chemistry in 55 | CAS: 530-40-5

Journal of Organic Chemistry published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H14N2O, Name: N,N-Diethylisonicotinamide.

Collins, Scott published the artcileAdditions of alkyllathanum triflates to carbonyl compounds: reactive organometallic nucleophiles, Name: N,N-Diethylisonicotinamide, the publication is Journal of Organic Chemistry (1990), 55(11), 3565-8, database is CAplus.

Addition of alkyl- or aryllithium compounds to lanthanum(III) triflate in ethereal solvents produces the title reagents RLa(O3SCF3)2 (R = Me, Bu, Ph) that undergo nucleophilic addition to carbonyl compounds under mild conditions. These reagents resemble alkylcerium halides in their reactions with enolizable carbonyl compounds but are more reactive. In particular, they are useful for the conversion of hindered, tertiary amides to ketones. 1H NMR spectroscopy was employed to clarify mechanistic aspects of this addition process. The title reagents actually appear to be a mixture of several species; formulation of their structure has proven elusive. However, in the presence of a tertiary amide, these species react to give a single, tetrahedral intermediate, which is quite stable in solution

Journal of Organic Chemistry published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H14N2O, Name: N,N-Diethylisonicotinamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics