Coordination-Driven Self-Assembly and Anticancer Activity of Molecular Rectangles Containing Octahedral Ruthenium Metal Centers was written by Vajpayee, Vaishali;Song, Young Ho;Yang, Yoon Jung;Kang, Se Chan;Kim, Hyunuk;Kim, In Su;Wang, Ming;Stang, Peter J.;Chi, Ki-Whan. And the article was included in Organometallics in 2011.SDS of cas: 53118-43-7 The following contents are mentioned in the article:
The synthesis of new 2+2 metallarectangle macrocycles 1–3 via coordination-driven self-assembly of octahedral arene Ru(II)-based acceptors and dipyridyl amide ligand donors is described. To evaluate their in vitro cytotoxic properties, preliminary biol. assays were carried out for various human cancer cell lines, and the results show that the cytotoxicity level of 3 is comparable or even greater in the cases of SK-hep-1 and HCT-15 than that of the reference drug cisplatin. This study involved multiple reactions and reactants, such as N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7SDS of cas: 53118-43-7).
N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.SDS of cas: 53118-43-7
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics