Synthesis and antimicrobial activity of 1,2-diaryl- and 2,3-diaryl-(2-aryl-3-n-arylamino)-1,2,3,4-tetrahydroquinazolin-4-ones was written by Sattarova, O. E.;Vizgunova, O. L.;Voronina, E. V.. And the article was included in Pharmaceutical Chemistry Journal in 2006.Safety of 2-Amino-N-(2-bromophenyl)benzamide The following contents are mentioned in the article:
A series of 2,3-diaryl, (2-aryl-3-N-arylamino)- and 1,2-diaryl-1,2,3,4-tetrahydroquinazolin-4-ones, e.g., I (R = Br or NO2) were obtained via reactions of arylamides and anthranilic acid phenylhydrazide or N-arylanthranilic acid amides with 5-bromo- or 5-nitrosalicylic aldehydes. One of these compounds was acetylated to obtain a triacetyl derivative The structures of the synthesized compounds were determined by spectral methods (1H NMR, IR) and their antimicrobial activity was evaluated. This study involved multiple reactions and reactants, such as 2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5Safety of 2-Amino-N-(2-bromophenyl)benzamide).
2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Safety of 2-Amino-N-(2-bromophenyl)benzamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics