New approach to the synthesis of polyfunctional isoquinolones was written by Nemazanyi, A. G.;Volovenko, Yu. M.;Silaeva, T. A.;Babichev, F. S.. And the article was included in Doklady Akademii Nauk Ukrainskoi SSR in 1989.Recommanded Product: 83909-69-7 The following contents are mentioned in the article:
The title isoquinolones I (R1 = H, R2 = NO2, R3 = H, Me, Ph, PhCH2, 4-MeOC6H4; R1 = Cl, R2 = H, R3 = H, Me; R1-R3 = H) were prepared in 54-93% yields by treating the corresponding benzamides II (R4 = H, Me, X = Cl, F) with CH2(CN)2 in DMF containing K2CO3. This study involved multiple reactions and reactants, such as N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7Recommanded Product: 83909-69-7).
N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Recommanded Product: 83909-69-7
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics