Aqueous phase mono-protection of amines and amino acids as N-benzyloxycarbonyl derivatives in the presence of β-cyclodextrin was written by Kumar, V. Pavan;Reddy, M. Somi;Narender, M.;Surendra, K.;Nageswar, Y. V. D.;Rao, K. Rama. And the article was included in Tetrahedron Letters in 2006.SDS of cas: 887757-51-9 The following contents are mentioned in the article:
A simple and selective protection of amines/amino acids with Cbz-Cl was achieved in aqueous phase with catalytic amounts of β-cyclodextrin in high yields at room temperature This reaction proceeds without the formation of any byproducts and has advantages over existing methods. This study involved multiple reactions and reactants, such as Benzyl (3-hydroxypropyl)(methyl)carbamate (cas: 887757-51-9SDS of cas: 887757-51-9).
Benzyl (3-hydroxypropyl)(methyl)carbamate (cas: 887757-51-9) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.SDS of cas: 887757-51-9
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics