Boron tribromide catalysed facile and efficient synthesis of 2,3-disubstituted Quinazolinone derivatives was written by Jaganmohan, Chikkanti;Rao, Vinti S. P.;Shiva Prakash, P.;Vinay Kumar, K. P.;Mohanty, Sandeep;Kumar, Jaydeep;Venkateswara Rao, B.;Raghunadh, Akula. And the article was included in Heterocyclic Letters in 2019.Recommanded Product: 34489-85-5 The following contents are mentioned in the article:
A simple, convenient synthetic protocols have been developed for the synthesis of 2,3-disubstituted quinazolinone derivatives I (R = Me, Ph, 4-methoxyphenyl, etc.) using borontribromide as efficient catalyst. This reaction proceeds under mild conditions. This method was found to be better method giving high yields. The present method shows some advantages such as short reaction times and enhanced selectivity. This study involved multiple reactions and reactants, such as 2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5Recommanded Product: 34489-85-5).
2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Recommanded Product: 34489-85-5
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics