Deep eutectic solvent mediated synthesis of quinazolinones and dihydroquinazolinones: synthesis of natural products and drugs was written by Ghosh, Suman Kr;Nagarajan, Rajagopal. And the article was included in RSC Advances in 2016.Application of 34489-85-5 The following contents are mentioned in the article:
A mild and greener protocol was developed to synthesize substituted quinazolinones and dihydroquinazolinones via deep eutectic solvent (DES) mediated cyclization with a series of aliphatic, aromatic, and heteroaromatic aldehydes in good to excellent yields. This greener strategy was further utilized to synthesize various quinazolinone natural products and drugs. This study involved multiple reactions and reactants, such as 2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5Application of 34489-85-5).
2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Application of 34489-85-5
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics