Fatty acid amides and anilides. Syntheses and antimicrobial properties was written by Bistline, R. G. Jr.;Maurer, E. W.;Smith, F. D.;Linfield, W. M.. And the article was included in Journal of the American Oil Chemists’ Society in 1980.HPLC of Formula: 730-25-6 The following contents are mentioned in the article:
A series of fatty acid amides and anilides was prepared; a number of compounds in the series were highly active against gram pos. bacteria but ineffective against gram neg. organisms. The N,N-dimethyl- and N,N-diethylamides of C12-C14 fatty acids had minimal inhibitory concentration (MIC) values of 100 ppm or less. Substituted anilides of C6-C11 fatty acids were active when the following groups were attached to the aromatic ring: 3,4-dichloro, 3-nitro, 4-nitro, 5-nitro-2-hydroxy, 4-chloro-3-nitro, and 2-hydroxy-5-nitro. Some of these compounds had a MIC value of 0.1 ppm. Significantly, the presence of soap did not reduce the activity of these bacteriostats, whereas polysorbate 80 at high concentrations deactivated the compounds This study involved multiple reactions and reactants, such as N-(3,4-Dichlorophenyl)octanamide (cas: 730-25-6HPLC of Formula: 730-25-6).
N-(3,4-Dichlorophenyl)octanamide (cas: 730-25-6) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.HPLC of Formula: 730-25-6
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics