NaNO2/I2 as an alternative reagent for the synthesis of 1,2,3-benzotriazin-4(3H)-ones from 2-aminobenzamides was written by Barak, Dinesh S.;Mukhopadhyay, Sushobhan;Dahatonde, Dipak J.;Batra, Sanjay. And the article was included in Tetrahedron Letters in 2019.COA of Formula: C13H11BrN2O The following contents are mentioned in the article:
An efficient transformation of 2-aminobenzamides to 1,2,3-benzotriazin-4(3H)-ones in the presence of sodium nitrite (NaNO2) and Iodine (I2) is described. The reaction is proposed to proceed via formation of nitrosyl halide that induces nitrosylation of the amino group of 2-aminobenzamide leading to diazotization followed by intramol. cyclization. This study involved multiple reactions and reactants, such as 2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5COA of Formula: C13H11BrN2O).
2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.COA of Formula: C13H11BrN2O
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics