O’Callaghan, C. N. published the artcileAnticancer agents XIII. Synthesis and antitumor activity of 2-iminochromene derivatives, SDS of cas: 15029-36-4, the publication is Proceedings of the Royal Irish Academy, Section B: Biological, Geological and Chemical Science (1979), 79B(6), 87-98, database is CAplus.
Iminochromenes I (R = H, 6-OMe, 7-OMe, 6-NO2, 6,8-Br2, 8-OEt, 8-OMe; R1 = H, alkyl, hydroxyalkyl, NHCSNHMe, optionally substituted Ph, anilino, acylamino, morpholino) were prepared by condensing salicylaldehydes with NCCH2CONHR1. II (R2 = OMe, OEt, OPr, R3 = H; R2 = H, R3 = OMe, OEt, OPr) were obtained by condensing salicylaldehydes with 1-cyanoacetyl-3,5-dimethylpyrazole. I, II, and related compounds had antitumor activity. Thus, I (R = 6-OMe, R1 = H) gave a mean survival time 131% of controls as 108 mg/kg in P 388 lymphocytic leukemia-infected mice.
Proceedings of the Royal Irish Academy, Section B: Biological, Geological and Chemical Science published new progress about 15029-36-4. 15029-36-4 belongs to amides-buliding-blocks, auxiliary class Nitrile,Amine,Aliphatic hydrocarbon chain,Amide, name is 2-Cyano-N-ethylacetamide, and the molecular formula is C5H8N2O, SDS of cas: 15029-36-4.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics