Culbertson, Townley P. published the artcileNew 7-substituted quinolone antibacterial agents. The synthesis of 1-ethyl-1,4-dihydro-4-oxo-7-(2-thiazolyl and 4-thiazolyl)-3-quinolinecarboxylic acids, Related Products of amides-buliding-blocks, the publication is Journal of Heterocyclic Chemistry (1987), 24(6), 1509-20, database is CAplus.
A series of 1-ethyl-1,4-dihydro-4-oxo-7-(4-thiazolyl)-3-quinolinecarboxylic acids e.g. I (R = NH2, MeNH, AcNCH2, Me2N, 3-pyridyl, morpholino, etc.; R1,R2 = H, F), and 1-ethyl-1,4-dihydro-4-oxo-7-(2-thiazolyl)-3-quinolinecarboxylic acids were prepared Also prepared was 10-[2-(aminomethyl)-4-thiazolyl]-9-fluoro-2,3-dihydro-3-methyl-7–oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid (II). Analogs with basic amine substituents on the thiazole moiety were found to have antibacterial activity.
Journal of Heterocyclic Chemistry published new progress about 14294-10-1. 14294-10-1 belongs to amides-buliding-blocks, auxiliary class Morpholine,Thiourea,Amine,Amide, name is Morpholine-4-carbothioamide, and the molecular formula is C5H10N2OS, Related Products of amides-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics