Adel M. Kamal El-Dean published the artcileNovel Synthesis, Reactions, and Biological Study of New Morpholino-Thieno[2,3-c][2,7]Naphthyridines as Anti-Cancer and Anti-Microbial Agents, COA of Formula: C2H4ClNO, the publication is Russian Journal of Bioorganic Chemistry, database is CAplus.
The biol. uses of 2,7-naphthyridines have sparked great attention in recent years. For this reason, a series of novel 2,7-naphthyridines derivatives was synthesized and explored their spectrum and biol. properties in this study. Compound I was prepared by the reaction of 1-Me piperidin-4-one with CS2, malononitrile, and triethylamine. The condensed I be converted to II by reaction with morpholine. Composite II was used as a starter in heterocyclic compound a series, such as the thieno[2,3-c][2,7]naphthyridines III (R = CN, COOEt, COPh, etc.). Authors used III (R = COOEt), III (R = CONH2) and III (R = CHO) as a precursor to create original heterocyclic moieties, namely: pyrimidothienonaphthyridino and pyridothieno naphthyridino in compounds A number of compounds for antimicrobial activity were examined against a variety of bacterial and fungal strains. In addition, some of these compounds showed anticancer activity in liver and cells of breast cancer.
Russian Journal of Bioorganic Chemistry published new progress about 79-07-2. 79-07-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Aliphatic hydrocarbon chain,Amide,Inhibitor, name is 2-Chloroacetamide, and the molecular formula is C2H4ClNO, COA of Formula: C2H4ClNO.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics