Bioactive compounds from medicinal plants: Focus on Piper species was written by Mgbeahuruike, E. E.;Yrjonen, T.;Vuorela, H.;Holm, Y.. And the article was included in South African Journal of Botany in 2017.Formula: C14H25NO The following contents are mentioned in the article:
This article reviews new discoveries related to the phytochem. and biol. activities of bioactive compounds from Piper species. It outlines the anticancer, anti-parasitic, and antimicrobial activities of Piper species in relation to drug discovery. The use of bioactive compounds from medicinal plants as therapeutic agents has been an important area in biomedical and natural product research. Piper species are effective medicinal plants used in folk medicine. They have traditionally been used to treat stomach ache, rheumatoid arthritis, diarrhea and other general infections, and their efficacy has been attributed to their bioactive compounds Bioactive compounds and extracts from Piper species have been examined and found to be of clin. importance for both malignant and non-malignant diseases. They have displayed pronounced efficacy as anticancer, antitumor and antimicrobial agents in various pharmacol. studies. They have been reported to possess anti-inflammatory, antioxidant, antibacterial, antifungal, and antimalarial activities. The alkaloids piperine, piperlongumine, guineensine, chabamide and pellitorine, which have been isolated from most Piper species, are able to inhibit the growth of cancer cell lines inducing apoptosis and acting as nuclear export inhibitors. These bioactive compounds can improve the effectiveness of chemotherapeutic drugs with minimal systemic toxicity to normal cells in cancer therapy. Pinoresinol, guineensine and other bioactive compounds from this species exhibited strong antimicrobial efficacy against various microorganisms including pathogenic Vibrio strains, which are often involved in host cell invasion during Vibrio cholera infection. The anticancer, antimicrobial and antimalarial properties of Piper species are compiled to support further exploration of their bioactive compounds for drug discovery. Biomedical and pharmacol. discoveries concerning their anticancer and antimicrobial properties are highlighted here for further clin. applications, which could pave the way for the proper therapeutic use of bioactive compounds and extracts from this plant species. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Formula: C14H25NO).
(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Formula: C14H25NO
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics