Wolczanski, Grzegorz published the artcileSelf-synthesizing models of helical proteins based on aromatic disulfide chemistry, Quality Control of 2418-95-3, the publication is Chemistry – A European Journal (2018), 24(49), 12869-12878, database is CAplus and MEDLINE.
A new method of synthesis of peptide conjugates with aromatic moieties substituted with two sulfhydryl groups at 1,3-positions is proposed. Amphiphilic peptides derivatized in such a way under oxidative conditions spontaneously form cyclic, covalent trimers and tetramers dominated by α-helical conformations. The tendency to form tri- or tetrahelical bundles depends on sequences of the peptides and on the oxidation conditions, pH, and additives.
Chemistry – A European Journal published new progress about 2418-95-3. 2418-95-3 belongs to amides-buliding-blocks, auxiliary class Chiral,Carboxylic acid,Amine,Aliphatic hydrocarbon chain,Ester,Amino acide derivatives, name is H-Lys(Boc)-OH, and the molecular formula is C7H5Cl2NO2, Quality Control of 2418-95-3.
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